For this project, we had to find how protein affects and causes different diseases. My group and I was given Parkinson's disease. We had to research what the disease was, how it is caused, where it happens in the body, and symptoms of it. We also had to research protein synthesis, what happens in the different steps and stages of it, and how it is related to the disease we were given. To present this project, we decided to make a website including all our research on Parkinson's and protein synthesis. You can find the link to our website below. https://stemparkinsons.weebly.com/
content
protein synthesis- The process by which amino acids are arranged into proteins through the involvement of ribosomal RNA, transfer RNA, messenger RNA, and various enzymes.
codon/anticodon- Codon is a sequence of three nucleotides that together form a unit of genetic code in a DNA or RNA molecule. Anticodon is a sequence of three nucleotides forming a unit of genetic code in a transfer RNA molecule, corresponding to a complementary codon in messenger RNA.
polymerase- An enzyme that brings about the formation of a particular polymer, especially DNA or RNA.
polypeptide chain- Each polypeptide chain consists of smaller sub-units or amino acids that are linked together. Polypeptides serve as the building blocks of proteins. A polypeptide can serve as a protein on its own.
proteins- Protein is an important component of every cell in the body. Our body uses protein to build and repair tissues. You also use proteins to make enzymes, hormones, and other body chemicals. Proteins are important building block of bones, muscles, cartilage, skin, and blood.
transcription- Transcription is the first step of protein synthesis, in which a particular segment of DNA is copied into RNA by the enzyme RNA polymerase.
translation- Translation is a step in protein synthesis where the genetic code carried by mRNA is decoded to produce the specific sequence of amino acids in a polypeptide chain.
alpha helix- The alpha helix is a common motif in the secondary structure of proteins and is a right hand-spiral conformation in which every backbone N−H group donates a hydrogen bond to the backbone C=O group of the amino acid located three or four residues earlier along the protein sequence.
beta sheet- Beta sheets are a common motif of regular secondary structure in proteins. They consist of beta strands connected laterally by at least two or three backbone hydrogen bonds, forming a generally twisted, pleated sheet.
amino acids- Amino acids are organic compounds containing amine and carboxyl functional groups, along with a side chain specific to each amino acid. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen, although other elements are found in the side chains of certain amino acids.
RNA- RNA stands for ribonucleic acid. RNA is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and DNA are nucleic acids, and, along with lipids, proteins and carbohydrates, constitute the four major macromolecules essential for all known forms of life.
mRNA- Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
tRNA- Transfer RNA (tRNA) is a type of RNA molecule that helps decode an mRNA sequence into a protein. tRNAs function at specific sites in the ribosome during translation.
reflection
I thought this project was interesting and I learned a lot about protein synthesis, proteins, Parkinson's, and many other things. I enjoyed this project over other past projects, and I feel that I cooperated a lot more, and had good work ethic. My group and I were very organized during the project and we split the work between us equally. We had few disagreements, but were able to resolve them quickly.